Using Raman Spectroscopy to Investigate the Molecular Level Characteristics of Endometriosis

Optics and Spectroscopy - Endometriosis is a benign gynecologic disorder. It is particularly common among young women and may make pregnancy difficult. In this study molecular level...     

Synthesis,characterization, duplex-DNA interactions,and anticancer activities of novel octahedral [Ni(phen)2(dppz-idzo)]2+ and [Co(phen)2(dppz-idzo)]3+ complexes

Two new octahedral [Ni(phen)₂(dppz-idzo)]²⁺ and [Co(phen)₂(dppz-idzo)]³⁺ complexes have been synthesized and characterized by CHN analysis, electrospray ionization-MS, nuclear magnetic resonance, and UV–Vis spectra. The DNA-binding ability of these complexes was spectrophotometrically, hydrodynamically, and electrophoretically evaluated which indicated that they strongly intercalate into the DNA double helix, and that both induced severe DNA damage in the presence of peroxide. The complexes also showed strong antiproliferative effect against HepG2 and MDA-MB-231 cells. By contrast, they were found to be inactive against the MCF-7 cell line. The ligand itself was found to be inactive against the cells tested.     

Microelectromechanical Systems for Nanomechanical Testing: Electrostatic Actuation and Capacitive Sensing for High-Strain-Rate Testing

Experimental Mechanics - There have been relatively few studies on mechanical properties of nanomaterials under high strain rates, mainly due to the lack of capable nanomechanical testing devices....     

A Sm(III) Coordination Polymer Containing 2,5-Furandicarboxylic Acid: Crystal Structure and Recognition of Oxalate in Water

Crystallography Reports - The {[Sm2(FDC)2](FDC) · 10H2O}n complex, where H2FDC is a 2,5-furandicarboxylic acid, has been prepared by hydrothermal reaction and structurally characterized by...     

物理演示实验教学在高素质新型军事人才培养中的作用

培养高素质新型军事人才是国防科技大学的核心任务之一.物理演示实验以直观、形象地演示物理现象为课程特色,可有效提高学员对物理规律、物理本质的直观认识和深刻理解,并引起学员的深入思考,在教学实践中可促进学员科学素质、综合能力和创新能力的提高.     

Modeling ExB drift transport in conceptual slot divertor configurations

At DIII-D, a slot divertor concept, called small-angle-slot (SAS), is under development, aiming to enable detachment at relatively low plasma edge density. We report on simulations using the SOLPS-ITER two-dimensional edge code to examine the performance of conceptual “SAS 2” slot configurations. The focus of the analysis is on E  ×  B drift effects on upstream density at detachment (UDD), with detachment marked by electron temperature T_e ≤ 3 eV at the outer strike point (OSP). With toroidal field such that radial E  ×  B drift carries particles from the OSP towards the private flux region (PFR), placing the OSP near the inner slot wall gives ≈20% lower UDD than having the OSP near the outer wall. The inner wall effectively traps the radial E  ×  B drift flux, resulting in low T_e and associated radial electric field in the PFR, and thus small losses from the slot to the inner target via poloidal E  ×  B drift flux. With toroidal field reversed such that radial E  ×  B drift is reversed, OSP placement near the inner wall gives ≈10% lower UDD than OSP placement near the outer wall. Although radial E  ×  B flux is from the OSP towards the outer wall, this flux largely escapes the slot, raising the UDD. A change in the slot shaping is suggested with the goal of eliminating such E  ×  B -driven particle losses from the slot.     

A Lumped Parameter Model of a Fibre-Reinforced Composite Plate with Temperature Dependence Based on Thermal Vibration Measurements

Experimental Mechanics - Background: Experimental modelling techniques are still rare for composite structures under complex thermal environments. Objective: In this paper, by taking a...     

A Disulfide Intercalator Toolbox for the Site‐Directed Modification of Polypeptides

A disulfide intercalator toolbox was developed for site‐specific attachment of a broad variety of functional groups to proteins or peptides under mild, physiological conditions. The peptide hormone somatostatin (SST) served as model compound for intercalation into the available disulfide functionalization schemes starting from the intercalator or the reactive SST precursor before or after bioconjugation. A tetrazole–SST derivative was obtained that undergoes photoinduced cycloaddition in mammalian cells, which was monitored by live‐cell imaging.